TDS Proteins API USP Co-Op

Location: Malvern, Pennsylvania, United States of America

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com.

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function

Career Programs

Job Sub Function

Non-LDP Intern/Co-Op

Job Category

Career Program

All Job Posting Locations

Malvern, Pennsylvania, United States of America

Job Description

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for TDS Proteins API USP Co-Op to be in Malvern, PA.

4 vacancies are currently available.

The Co-op term is six months typically from January to June, 2027 (flexible).

Full time requirement (40 hours per week) Fully On-site.

Purpose

The TDS Proteins Development API organization is seeking highly motivated Co-Op candidates to support Upstream Process Development initiatives focused on mammalian cell culture, bioreactor process development, process modeling, advanced data analytics, and manufacturing scale-down models.

This opportunity provides hands-on experience supporting the development and optimization of CHO cell culture processes, dynamic feeding strategies, media and process parameter studies, product quality assessments, and automated high-throughput bioreactor systems. Co-Ops will collaborate with scientists, engineers, and internal and external partners to generate, analyze, and interpret data that advance upstream process understanding, scalability, productivity, and manufacturing readiness.

You will be responsible

Depending on the assigned project, responsibilities may include:

Supporting upstream process development activities involving CHO cell culture, media development, bioreactor operation, and process optimization.

Designing and executing shake-flask, small-scale bioreactor, and automated high-throughput bioreactor studies.

Developing correlations between real-time biocapacitance signals and offline viable cell density measurements across different CHO cell lines and media conditions.

Supporting the development and implementation of dynamic feeding strategies that adjust nutrient feed rates based on real-time cell density measurements.

Evaluating the impact of media components, feeding strategies, and process parameters on cell culture performance and product quality attributes, including titer, viability, productivity, and galactosylation.

Supporting development and characterization of small-scale models that represent manufacturing-scale cell culture processes.

Comparing small-scale and manufacturing-scale process performance to identify conditions that support appropriate process representation and scalability.

Performing advanced analytics on historical and experimental process and spent-media datasets to identify actionable insights.

Developing and applying mechanistic, data-driven, or hybrid models to explain and predict process outcomes such as end-of-run titer and cell-specific productivity.

Designing experiments informed by model outputs, process knowledge, and statistical design principles.

Analyzing, visualizing, interpreting, and presenting experimental results using analytical and statistical techniques.

Participating in technical discussions, design of experiments, and problem-solving activities to address knowledge gaps.

Collaborating with internal and external partners and actively participating in recurring project meetings.

Maintaining laboratory notebooks, technical reports, datasets, and other documentation in accordance with established guidelines.

Providing additional laboratory, analytical, and project support as needed.

Qualifications / Requirements

Completion of Undergraduate Freshman year at an accredited University is required.

Currently pursuing a Bachelor’s, Master’s or PhD degree in Biology, Chemistry, Analytical Chemistry, Biochemistry, Molecular Biology, Microbiology, Biotechnology, Chemical, Biological, Biomedical Engineering, Pharmaceutical Sciences, Related scientific or engineering disciplines.

Have a cumulative GPA of 3.0 or higher, which is reflective of all college coursework.

Experience with aseptic mammalian cell culture techniques is required for laboratory-focused assignments.

Some experience with bioreactor operation is required for bioreactor-focused assignments.

Strong analytical, quantitative, and problem-solving skills are required.

Ability to analyze complex experimental or process data and draw data-driven conclusions.

Ability to balance multiple projects and priorities while delivering results.

Ability to work independently as a self-starter while contributing effectively to team objectives.

Strong written and verbal communication skills, including the ability to present technical findings.

Candidates must be legally authorized to work in the United States and must not require sponsorship for employment visa status now or in the future.

Permanently authorized